SYNTHESIS OF COMPOSITE MATERIALS BASED ON HYDROXYAPATITE AND POLYVINYL ALCOHOL AND ESTABLISHING THE INFLUENCE OF PRODUCTION CONDITIONS

10.25712/ASTU.1811-1416.2024.01.004

Abstract

It is known that the development of biomedical technologies increases the demand for the creation of biocompatible materials that would have similar properties to bone tissue and are suitable for its implantation. Many composite materials are multiphase systems consisting of a polymer matrix and an inorganic component of various shapes and sizes. The polymer component is necessary to improve the mechanical and biocompatible properties. This component can be represented by a biocompatible, macroporous and non-toxic polymer, the breakdown products of which will be accepted by the body as ordinary metabolites and will be excreted from it. The inorganic component can be represented by hydroxyapatite, the composition and structure of which is similar to bone apatite, which ensures mutual integration and the formation of chemical bonds between the damaged bone and the implant. Under physiological conditions, a calcium phosphate layer is formed, which ensures the biological activity of hydroxyapatite. The calcium phosphate layer can be characterized by different structures and compositions, as it interacts with ions found in the physiological fluids of the body.